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Título : Effect of Pulsed Light treatment on beta-lactoglobulin immunoreactivity
Autor : Orcajo, Janire; Lavilla, Maria; Martinez de Maranon, Inigo
Resumen : This study investigates the effects of different Pulsed Light (PL) treatments (from 4 to 16 J/cm(2) of total fluence) on the immunoreactivity and digestibility of beta-lactoglobulin (beta-lg), one of the main allergens in milk. Our findings show that PL significantly decreases the recognition of beta-lg by both IgG and IgE, up to an average 85\% and 45\% of reduction, respectively, compared to the untreated protein, especially when the protein is treated in a solution at pH 6.8. The reduction in IgE binding was also evidenced in acid and sweet whey. However, in this product, the presence of other components could protect the protein from denaturation by the effect of light, and only a maximum reduction of 37\% in IgE-binding was achieved. Moreover, this work has confirmed that PL treatment may also contribute to accelerate protein digestibility, under simulated gastric conditions (pepsin digestion). Our results suggest that this technology, under the suitable conditions, could be used as a valuable alternative treatment for reducing the immunoreactivity of allergenic proteins. Also, we reveal new findings on the allergen modifications due to food processing, that will improve knowledge-based ways to managing allergens risks in food industry.
Palabras clave : beta-lactoglobulin; Pulsed light (PL); IgE; Immunoreactivity; Digestibility; FOOD PROTEINS; INACTIVATION; ALLERGEN; EQUILIBRIUM; BINDING; DIMER
Fecha de publicación : 2019
Editorial : ELSEVIER
Tipo de documento: Article
Idioma: 
DOI: 10.1016/j.lwt.2019.05.129
URI : http://dspace.azti.es/handle/24689/951
ISSN : 0023-6438
E-ISSN: 1096-1127
Patrocinador: Spanish Ministry of Economy and Competitivity [RTC-2015-3818-2]
Basque Government (ALERTEC project)
Aparece en las tipos de publicación: Artículos científicos



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