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Title: Zebrafish dives into food research: effectiveness assessment of bioactive compounds
Authors: Caro, M.; Iturria, I.; Martinez-Santos, M.; Pardo, M. A.; Tueros, I.; Navarro, V.; Rainieri, S.
Citation: FOOD \& FUNCTION, 2016, 7, 2615-2623
Abstract: Zebrafish have been traditionally used in ecotoxicology and developmental biology. However, due to the advances in available methodologies and the similitude with mammals, it has been increasingly used in other fields. One of the most recent fields using zebrafish is food research, being the focus of this review. Most relevant and recent publications including food component toxicity and key metabolic effects together with effectiveness on some zebrafish disease models have been reviewed. This model is a good intermediate tool between in vitro and rodent models, because it provides information from a complete organism in a fast and cost-effective manner. Definitely, in the near future, we will see this model being used by the ingredient suppliers and scientists in order to show the potential impact on health of several compounds.
Keywords: DANIO-RERIO LARVAE; ACTIVITY IN-VITRO; CELL-CYCLE; ANTIATHEROSCLEROTIC ACTIVITY; TRANSCRIPTOME ALTERATIONS; ENDOCRINE DISRUPTION; BONE RESEARCH; MODEL SYSTEM; BISPHENOL-A; EMBRYO TEST
Issue Date: 2016
Publisher: ROYAL SOC CHEMISTRY
Type: Review
Language: English
DOI: 10.1039/c6fo00046k
URI: http://dspace.azti.es/handle/24689/188
ISSN: 2042-6496
E-ISSN: 2042-650X
Funder: Basque Government funding
Fundacion Inaki Goenaga - Centros Tecnologicos
Economic Development and Competitiveness Department of the Basque Government
Appears in Publication types:Artículos científicos



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